唐氏综合症儿童的营养 - - 当前知识,挑战和临床建议 - - 叙述性综述
Sebastian Żur1, Adam Sokal1, Wiktoria Staśkiewicz-Bartecka2
1Department of Human Nutrition, Department of Dietetics, Faculty of Public Health in Bytom, Medical University of Silesia in Katowice, Jordana 19, 41-808 Zabrze, Poland.
Healthcare (Basel, Switzerland)
|September 13, 2025
概括
患有唐氏综合征 (DS) 的儿童因代谢和发育因素而面临独特的营养挑战. 制定特定的饮食指南对于优化他们的健康和福祉至关重要.
科学领域:
- 儿童营养学 儿童营养学
- 遗传学和新陈代谢
- 唐氏综合征研究 唐氏综合征研究
背景情况:
- 患有唐氏综合征 (DS) 的儿童经历了由遗传,代谢和发育因素引起的复杂营养问题.
- 现有的营养指南不足以满足患有DS的儿童的特殊需求.
- 本综述探讨了有关DS儿童营养状况,挑战和干预措施的现有证据.
研究的目的:
- 总结有关唐氏综合征儿童营养状况,挑战和治疗策略的科学证据.
- 强调临床影响,并为医疗保健专业人员提供实际建议.
- 突出需要针对特定人群的饮食指南.
主要方法:
- 在PubMed,Scopus,Web of Science和Google Scholar (1993年至2025年6月) 进行了全面的文献搜索.
- 根据PRISMA协议,选出了35篇同行评审文章,包括原始研究,评论和专家指南.
- 研究被按能量需求,并发症,食困难,营养需求和干预措施分类.
主要成果:
- 患有DS的儿童的新陈代谢率较低,身体成分发生变化,增加肥胖和缺陷的风险.
- 像甲状腺功能低下症和腹腔疾病这样的并发症使饮食管理复杂化.
- 食困难很常见,影响饮食质量,关键营养物质引起关注,包括蛋白质,欧米茄-3脂肪酸,纤维,维生素B12和D,铁和抗氧化剂.
结论:
- 迫切需要为患有唐氏综合征的儿童制定基于证据的,针对特定人群的饮食指南.
- 个性化,多学科和积极的临床营养护理是必不可少的.
- 进一步的研究,特别是干预研究,对于改善健康结果至关重要.
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