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在骨关节炎Synoviocytes的PI-PLC γ1 mRNA中,因特龙保留的分子基础

Alessia Mariano1, Daniel D'Andrea2, Roberto Mattioli1

  • 1Department of Biochemical Sciences, Sapienza University of Rome, P.le Aldo Moro, 5, 00185 Rome, Italy.

International journal of molecular sciences
|September 13, 2025
PubMed
概括

在PI-PLC γ1 mRNA中的内保留 (IR) 与骨关节炎协同细胞中的CELF1蛋白有关. 本研究探讨了IR的分子机制及其在疾病中的作用.

关键词:
这是一种CUG结合蛋白.埃拉夫类家族1 (CELF1) 种类通过RNA-seq分析进行分析.个体间的变异性.内部保留 (IR) 是指内在的保留.骨关节炎 (OA) 是一种酸丁伊诺醇脂酶C γ1 (PI-PLC γ1) 是一种

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