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Updated: Jan 18, 2026

Generation of Native, Untagged Huntingtin Exon1 Monomer and Fibrils Using a SUMO Fusion Strategy
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Generation of Native, Untagged Huntingtin Exon1 Monomer and Fibrils Using a SUMO Fusion Strategy

Published on: June 27, 2018

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卷状卷状结构调解了亨廷丁的细胞间传播

Marco Bosica1, Chiara Grasselli1, Andrea Panfili1

  • 1Istituto di Ricerche Farmacologiche Mario Negri IRCCS, 20156 Milano, Italy.

International journal of molecular sciences
|September 13, 2025
PubMed
概括

亨廷顿病 (HD) 涉及亨廷丁蛋白 (Htt) 的聚合. 在HTT中,卷曲-卷曲 (Cc) 结构是其细胞间传播和细胞吸收的关键,这表明Cc形成是治疗点.

关键词:
聚合方式 聚合方式 聚合方式狩猎 狩猎 狩猎 狩猎类似子的传播方式.

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