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Updated: Jan 18, 2026

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在LINE-1ORF2p中核基转移的机制由QM/MM模拟揭示出来

Igor V Polyakov1, Kirill D Miroshnichenko1, Tatiana I Mulashkina1,2

  • 1Chemistry Department, Lomonosov Moscow State University, 119991 Moscow, Russia.

International journal of molecular sciences
|September 13, 2025
PubMed
概括

长间隔元素-1 (L1) 逆转录酶 (RT) 使用单个Mg2+离子进行DNA延长. 这项研究揭示了一步核类转移机制,没有第二个催化金属离子.

关键词:
在DNA延长过程中,Mg2+ 阴离子在ORF2p中,ORF2p是指ORF2p.QM/MM MD QM/MM MD MD 是一个数字.逆转录酶活动的逆转录酶活动.

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