在西班牙的二次预防中脂质谱管理:来自西班牙BDCAP注册表 (LIPIDSPAIN) 的数据
Miguel García-Villarino1,2,3, Carmen Lambert2, Tomás González-Vidal2,4
1Department of Medicine, University of Oviedo, 33003 Oviedo, Spain.
Journal of clinical medicine
|September 13, 2025
概括
在西班牙,许多接受二次心血管预防降脂治疗的患者仍然无法达到LDL胆固醇目标. 组合疗法更有效,但需要更密集的策略来更好地降低心血管风险.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 药物治疗 药物治疗
背景情况:
- 实现低密度脂蛋白胆固醇 (LDL-C) 目标对于二次心血管疾病预防至关重要.
- 临床指南建议采取积极的降脂策略,但许多患者无法达到目标的LDL-C水平.
- 这项研究调查了西班牙二次预防患者的脂质配置管理.
研究的目的:
- 评估西班牙二次预防患者的脂质配置管理.
- 分析2019-2023年降脂疗法和LDL-C水平的趋势.
- 识别治疗和实现目标的区域差异.
主要方法:
- 使用西班牙初级保健临床数据库 (BDCAP) 从2019-2023年进行的重复横截面研究.
- 包括先前患有缺血性心脏病,中风或外周动脉疾病的患者在降脂治疗中.
- 分析治疗类型,LDL-C水平,人口因素和区域差异.
主要成果:
- 在2023年,超过150万患者接受了降脂药物用于二次预防.
- 组合治疗的使用从2019年到2023年显著增加.
- 只有33.7%的LDL-C<70 mg/dL,65.6%的LDL-C<100 mg/dL,而组合治疗的疗效更高.
结论:
- 尽管联合治疗的使用增加,但西班牙许多二次预防患者没有达到LDL-C目标.
- 在治疗覆盖率方面存在显著的区域差异.
- 为了最大限度地降低心血管风险,需要更密集的脂质管理和遵守指导方针.
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