对于斯乔格伦病的营养干预:系统性审查
Fernanda Luiza Araújo de Lima Castro1, Joyce Elisa Heredia2, Lauren Frenzel Schuch3
1Department of Oral Surgery, Pathology, and Clinical Dentistry, School of Dentistry, Universidade Federal de Minas Gerais, Av. Pres. Antônio Carlos, 6627, Room 3204, Belo Horizonte 31270-910, Brazil.
Nutrients
|September 13, 2025
概括
营养干预措施显示出对控制Sjögren病 (SD) 症状的潜力. 然而,目前的证据不足以确定SD患者口服症状管理的具体饮食建议.
科学领域:
- 营养科学 营养科学
- 免疫学 免疫学 免疫学
- 类风湿病学 类风湿病学
背景情况:
- 对于Sjögren病 (SD) 的管理,缺乏针对Sicca症状的标准化指南.
- 对SD的营养干预措施的有效性尚未得到充分证实.
研究的目的:
- 系统地审查饮食干预措施对Sjögren病口腔干燥和眼睛干燥的影响.
- 评估营养策略对SD的唾液流和眼睛干燥的影响.
主要方法:
- 从多个数据库和灰色文献中对人类和动物研究进行系统审查.
- 描述性分析来自19项包括研究的数据.
- 评估方法质量和主要结果,如唾液流量和施尔默测试结果.
主要成果:
- 动物模型显示了卡路里限制,无质饮食,低脂肪饮食和特定补充剂的好处.
- 高和脂肪饮食对动物模型的唾液流量产生了负面影响,并增加了炎症.
- 人类研究对包括维生素,草药,无质,液体和植物性饮食在内的干预措施提出了混合的结果.
结论:
- 饮食管理可以为Sicca症状和Sjögren病的营养状况提供好处.
- 目前没有足够的证据来推针对SD口腔症状的特定饮食干预措施.
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