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Updated: Jan 18, 2026

Sample Preparation to Bioinformatics Analysis of DNA Methylation: Association Strategy for Obesity and Related Trait Studies
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Sample Preparation to Bioinformatics Analysis of DNA Methylation: Association Strategy for Obesity and Related Trait Studies

Published on: May 6, 2022

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特定途径的多基因评分大大增加了影响肝脏生物标志物的基因脂肪相互作用的发现

Kenneth E Westerman1, Daniel I Chasman2, W James Gauderman3

  • 1Clinical and Translational Epidemiology Unit, Massachusetts General Hospital, Boston, MA, USA; Department of Medicine, Harvard Medical School, Boston, MA, USA; Programs in Metabolism and Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.

HGG advances
|September 13, 2025
PubMed
概括

路径特定的多基因评分 (pPGS) 揭示了影响肝脏生物标志物的新型基因-脂肪性相互作用. 这些分数提供了比标准多基因分数 (PGS) 更易于解释的发现,以了解复杂的基因环境相互作用.

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