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Updated: Jan 18, 2026

Assays for the Degradation of Misfolded Proteins in Cells
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在α-synuclein分离和聚合动态中竞争的护手通路.

Nicola K Auld1, Shannon McMahon1, Nicholas R Marzano1

  • 1Molecular Horizons and School of Science, University of Wollongong, Wollongong, New South Wales, Australia.

Protein science : a publication of the Protein Society
|September 13, 2025
PubMed
概括

小热冲击蛋白 (sHsps) 和 Hsp70 陪伴蛋白不能一起分解α-synuclein 纤维. 单体α-synuclein压倒了Hsp70,阻碍了它在神经退行性疾病中清除有毒蛋白质聚合物的能力.

关键词:
这就是Hsp2727的原因.Hsp70 系统系统拆分 分散 分散 分散.分子的陪伴者是分子的陪伴者.αB-晶素的使用.α-Synuclein 是一种蛋白质.

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