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酸胆聚合物结合提高了蛋白质治疗药物的制药性能

Jie Ren1, Amin Haghighat Naeini2, Nishant Kumar2

  • 1Department of Chemical and Biomolecular Engineering, University of California, Los Angeles, Los Angeles, California 90095, United States.

Biomacromolecules
|September 13, 2025
PubMed
概括

这项研究使用聚合物-蛋白质结合来改善治疗性蛋白质. 较长的聚合物链显著降低了免疫反应,并延长了蛋白质半衰期,提高了治疗的有效性.

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