MASCC/ISOO临床实践陈述:免疫治疗的口服并发症的管理
Eduardo R Fregnani1, Joel B Epstein2,3, Nicole M A Blijlevens4
1Centro de Oncologia Molecular, Instituto de Ensino E Pesquisa, Hospital Sírio-Libanês, São Paulo, SP, Brazil.
概括
本临床实践声明为接受免疫治疗的患者管理口腔并发症提供了指导. 它详细介绍了常见的副作用和推的治疗方法,以改善患者的舒适性和口腔功能.
科学领域:
- 在瘤学瘤学.
- 免疫治疗是一种免疫疗法.
- 口腔医学是指口腔医学.
背景情况:
- 在接受癌症治疗的患者中,口腔并发症很常见,特别是在使用较新的免疫疗法时.
- 管理这些副作用对于维持治疗坚持和患者的生活质量至关重要.
研究的目的:
- 开发一个简洁的临床实践陈述 (CPS) 用于管理免疫治疗的瘤患者的口腔并发症.
- 为临床医生提供必要的实用信息,以提供最佳的护理标准.
主要方法:
- 对免疫疗法药物及其相关口服毒性的文献综述.
- 在MASCC/ISOO的口腔护理研究小组的专家之间达成共识.
- 整合现有文献,从类似的口腔疾病中推断,以及临床经验.
主要成果:
- 口腔免疫相关的不良事件 (irAEs) 包括粘膜/牙状况,失水症,失症和异口症.
- 管理策略是基于症状严重程度,常用的是局部类固醇/免疫调节剂和麻醉剂.
- 医疗保健中心提供有关免疫治疗期间口腔护理和牙科管理的指导.
结论:
- 免疫疗法诱导的口腔毒性的有效管理可以缓解不适,促进愈合,并恢复口腔功能.
- 医疗和口腔卫生专业人员之间的协作方法对于最佳的患者结果至关重要.
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