相关实验视频

Updated: Jan 17, 2026

In-vitro Reconstitution of Bacterial Ubiquitination and VCP/p97-mediated Elimination
07:58

In-vitro Reconstitution of Bacterial Ubiquitination and VCP/p97-mediated Elimination

Published on: January 2, 2026

107

线性ubiquitin机械的致病酸化导致炎症体传感器退化

Yang Yu1, Shanshan Yu2, Zhe Lu1

  • 1Laboratory of Pathogen Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China; Medical School, University of Chinese Academy of Sciences, Beijing 101408, China.

Cell reports
|September 13, 2025
PubMed
概括

结核菌的PknG激酶通过向LUBAC复合体来破坏宿主免疫力. 这种细菌蛋白质可以防止炎症酶激活,通过颠覆细胞防御机制来帮助持续感染.

关键词:
科普:分子生物学 分子生物学结核病菌菌菌的结核病菌的结核病菌.一些炎症一些炎症细胞内免疫监测 细胞内免疫监测线性无处不在链组装复合体,LUBAC.蛋白质激酶G,PknG 和蛋白质激酶G.无处不在的化

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