比较生活的简单7和生活的基本8与心脏衰竭的风险
Inge G van Loon1, Yvonne T van der Schouw2, M Louis Handoko3
1Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands; Department of Rehabilitation Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.
JACC. Advances
|September 13, 2025
概括
较高的心血管健康 (CVH) 评分,以生活必需品8 (LE8) 衡量,显著降低心力衰竭 (HF) 风险. LE8分数显示了与HF风险的分级关联,突出了其在心血管健康评估中的实用性.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 预防医学 预防医学
背景情况:
- 改善心血管健康 (CVH) 与降低心力衰竭 (HF) 风险有关.
- 生命的基本8 (LE8) 是一个全面的评分,评估8个关键的健康因素和行为.
研究的目的:
- 评估LE8得分与患心力衰竭的风险之间的关联.
- 将LE8评分系统与其前身Life's Simple 7 (LS7) 的评分系统进行比较.
主要方法:
- 利用了来自欧洲前性癌症和营养调查-荷兰 (EPIC-NL) 队列37,803名参与者的数据.
- 计算LE8分数 (0-100) 并将CVH分类为低,中等和高.
- 员工调整了考克斯的比例危险模型来分析LE8分数和HF风险,并将CVH从LS7重新分类到LE8.
主要成果:
- 高CVH与低CVH相比,与HF风险降低82%有关.
- 在LE8和LS7之间观察到CVH分类的显著差异,LE8将许多参与者重新分类为中度CVH.
- 确定了LE8得分与HF风险之间的分级,非线性关联,特别是对于中度的CVH水平.
结论:
- LE8和LS7评分系统在他们的心血管健康分类上有所不同.
- 在LE8得分和HF风险之间存在强烈的反向关系,表明在得分范围内的分级效应.
- LE8评分提供了对高温风险的细微评估,表明了使用简化分类的潜在局限性.
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