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可归因于估计的膜过率的心血管疾病负担:来自ATTICA研究 (2002-2022) 的见解

Evangelia Damigou¹, Matilda Florentin², Christina Chrysohoou³

¹Department of Nutrition and Dietetics, School of Health Sciences and Education, Harokopio University, Athens 17676, Greece.

Annals of epidemiology

|September 13, 2025

概括

慢性病 (CKD) 显著增加了心血管疾病 (CVD) 的风险. 管理CKD可以预防大量心血管疾病病例,突出其公共卫生的重要性.

科学领域:

腎臟病學 (nephrology) 是一種醫學.
心脏病学心脏病学
公共卫生公共卫生

背景情况:

慢性病 (CKD) 是一个日益严重的全球健康问题.
慢性病是心血管疾病 (CVD) 的已知危险因素.
了解CKD对心血管疾病的负担对于公共卫生战略至关重要.

研究的目的:

估计可归因于慢性病 (CKD) 的心血管疾病 (CVD) 负担.
调查这种心血管疾病负担是否因不同人口特征而有所不同.

主要方法:

在基线无心血管疾病的1988名成年人的长度研究 (2002-2022年) (ATTICA研究).
根据KDIGO指南使用eGFR ≤ 60mL/min/1.73m2定义的CKD.
使用WHO-ICD-10评估的心血管疾病事件;使用Miettinen公式计算的人口归因分数.

主要成果:

在基线时,CKD的患病率为4.7%.
36.1%的参与者在20年内患有心血管疾病;77%的CKD患者患有心血管疾病,而34%的CKD患者没有.
大约6%的新心血管疾病病例可以通过管理CKD来预防;根据性别和并发症观察到的差异.

结论:

慢性脏病对心血管疾病的负担作出了重大贡献.
有效的CKD管理有可能减少心血管疾病发病率.
在公共卫生倡议中应优先考虑CKD,特别是在心血管健康方面.

关键词:

心血管疾病是什么心血管疾病慢性脏疾病慢性脏疾病疾病负担疾病负担人口可归因的分数.美国GFRGFR

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