患有外周动脉疾病的患者心肌梗塞的危险因素
Karsten Keller1, Volker H Schmitt2, Lukas Hobohm1
1Department of Cardiology, University Medical Center Mainz (Johannes Gutenberg-University Mainz), Mainz, Germany; Center for Thrombosis and Hemostasis (CTH), University Medical Center Mainz (Johannes Gutenberg-University Mainz), Mainz, Germany.
International journal of cardiology
|September 13, 2025
概括
在外周动脉疾病 (PAD) 患者的心肌梗塞 (MI) 显著增加死亡风险. 这项研究发现MI发生在PAD患者的0.9%,死亡率高出10倍,突出了关键的风险因素.
科学领域:
- 心血管医学 心血管医学
- 血管外科 血管外科
- 流行病学 流行病学
背景情况:
- 周围动脉疾病 (PAD) 是一种普遍的疾病,由于动脉样硬化,降低下肢血流.
- 患有PAD的患者面临肢体并发症和主要心血管事件的风险增加,包括心肌梗塞 (MI).
研究的目的:
- 研究因外周动脉疾病 (PAD) 住院的患者心肌梗塞 (MI) 的发生率和结果.
- 在PAD患者群体中确定与MI相关的独立风险因素.
主要方法:
- 利用德国全国范围内的2005-2020年住院患者数据.
- 包括所有因PAD入院的患者,分层对心脏病的存在进行分层.
- 分析了人口统计数据,并发症和住院病例死亡率.
主要成果:
- 分析了超过280万名PAD患者病例;0.9%的人经历了心脏病发作.
- 患有心脏病发作的PAD患者年龄较大 (≥70岁),并具有更严重的并发症概况.
- 住院病例死亡率在患有心脏病的PAD患者中是十倍以上 (29.0%对2.7%).
结论:
- 心肌梗塞 (MI) 仅影响一小部分外围动脉疾病 (PAD) 患者,但会大大增加死亡率.
- 在PAD患者中,肌痛性心脏病的独立风险因素包括晚年 (≥70岁),糖尿病,高脂血症,肺部疾病和癌症.
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