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Updated: Jan 6, 2026

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人工智能辅助药物重新定位用于人类肝纤维化

Yuan Guan1, Lu Cui2, Jakkapong Inchai1,3

  • 1Department of Anesthesiology, Pain and Perioperative Medicine, Stanford University School of Medicine, Stanford, CA, 94305, USA.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|September 14, 2025
PubMed
概括

这项研究使用人工智能联合科学家和人类肝脏器官重新定位了治疗肝纤维化的药物. 两种AI推的药物,包括Vorinostat,显示出显著的抗纤维菌作用,并促进肝脏再生.

关键词:
人工智能的人工智能肝脏有机体 有机体肝脏纤维化 肝脏纤维化

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Chronic liver disease significantly impacts drug metabolism due to alterations in hepatic blood flow and enzyme accessibility. This disruption affects the body's pharmacokinetics—the movement and processing of drugs within the system. Key enzymes crucial for metabolizing medications become less accessible, changing how drugs are processed and utilized. Furthermore, liver disease influences the synthesis of plasma proteins, such as albumin and globulins, which play critical roles in drug...
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