除外注射类固醇注射与口服治疗相比,用于腰部神经根部疼痛 - - 一项比较有效性研究
Nishtha Jain1, Vijay Sardana1, Usha Daria2
1Department of Neurology, Government Medical College, Kota, Rajasthan, India.
Neurology India
|September 14, 2025
概括
与单独的口服药物相比,在口服药物中添加外周内皮质类固醇注射可以提供优异的松性激光病的疼痛缓解. 这种综合方法在治疗慢性脊柱疼痛方面提高了患者的生活质量.
科学领域:
- 疼痛管理 疼痛管理
- 神经学 神经学
- 干预性疼痛医学 干预性疼痛医学
背景情况:
- 脊柱疼痛是一种普遍的慢性疼痛障碍.
- 目前的治疗方法包括保守的方法,干预和手术.
- 脊椎骨干细胞病常常呈现耐火性疼痛,需要有效的治疗策略.
研究的目的:
- 为了评估外围注射类固醇注射与 lumbosacral radiculopathy 的口服药物结合的疗效.
- 为了比较结合外围注射类固醇和口服药物的有效性与单独口服药物的有效性.
- 评估对耐火性腰椎神经根基病变患者疼痛缓解和生活质量的影响.
主要方法:
- 预期的观察性研究设计.
- 确诊的 lumbosacral radiculopathy 患者接受了 epidural 类固醇注射加上口服药物或升级口服药物.
- 疼痛评分 (视觉模拟尺度和功能评分指数) 在治疗前和治疗后进行了比较.
主要成果:
- 两个治疗组在6个月后显著减少了疼痛和功能评分.
- 组合治疗组在出院和1个月后期显示出统计学上显著的改善.
- 在3个月和6个月的组之间没有观察到疼痛评分的显著差异.
结论:
- 外周注射类固醇注射与口服药物和单独口服药物都对腹神经激光病有效.
- 与单独服用口服药物相比,联合治疗提供了优越的短期止痛疗法.
- 进一步的研究可能会探索长期的比较疗效.
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