预测来自社区和医院来源的沿海水域的诺罗病毒污染和抗菌素耐药性
Thomas W Clough1, Reshma Silvester2, Jessica Kevill2
1School of Ocean Sciences, Bangor University, Marine Centre Wales, Menai Bridge, LL59 5AB, UK.
Water research
|September 14, 2025
概括
医院的废水将致病病毒和抗菌素耐药性 (AMR) 生物释放到水环境中. 水力动力学建模量化了风险,揭示了夏季休期间的重大病原体暴露,特别是来自综合下水道溢出.
科学领域:
- 环境科学 环境科学
- 公共卫生 公共卫生
- 微生物学 微生物学
背景情况:
- 由于病原病毒和抗菌素耐药性 (AMR) 生物体进入水环境,医院的废水对公共卫生构成重大风险.
- 了解病原体在近海环境中的传播和命运至关重要,但人们对此了解甚少.
研究的目的:
- 用水力动力学建模量化沿海地区的医院衍生的废水病原体对人类的暴露风险.
- 在一年内分析诺罗病毒 (NoV) 和AMR基因的分散和命运,考虑季节,潮和加载率.
主要方法:
- 利用水力动力学建模来模拟病原体从三个医院扩散到沿海地区.
- 专注于沿淡水-河岸-海洋连续的诺罗病毒 (GI & GII) 和AMR基因.
- 评估了季节,潮模式和病原体载荷率对分散和命运的影响.
主要成果:
- 综合下水道溢出 (CSO) 贡献了 41% 的总医院衍生的病毒负载到沿海地区.
- 在游泳场所出现诺罗病毒 (NoV) GI 超标的可能性很大,夏季的概率为59%.
- 贝类中NOV和AMR的生物积累对消费者构成健康风险.
结论:
- 医院产生的废水对沿海水质和公共卫生产生重大影响,特别是在夏季.
- 需要先进的治疗,预测建模和监管调整,以减轻来自医院废水的风险.
- 水力动力学建模在量化废水衍生病原体对人类暴露风险方面是有效的.
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