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相关概念视频

Bone Disorders01:29

Bone Disorders

5.1K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
5.1K
Bone Remodeling01:40

Bone Remodeling

40.3K
Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
40.3K
Osteoclasts in Bone Remodeling01:31

Osteoclasts in Bone Remodeling

3.9K
Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during...
3.9K
Hormones and Bone Tissue01:17

Hormones and Bone Tissue

3.7K
The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
3.7K
What is the Skeletal System?01:02

What is the Skeletal System?

56.8K
Overview
56.8K
Role of Vitamins in Maintaining Bone Health01:25

Role of Vitamins in Maintaining Bone Health

5.0K
The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
5.0K

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相关实验视频

Updated: Jan 17, 2026

Author Spotlight: Integrating Traditional Chinese Medicine with Modern Pharmacology and Genomics for Assessing Postmenopausal Osteoporosis in Mice
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Author Spotlight: Integrating Traditional Chinese Medicine with Modern Pharmacology and Genomics for Assessing Postmenopausal Osteoporosis in Mice

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骨质疏松症

Carrie Ye1, Peter Ebeling2, Gregory Kline3

  • 1Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada; Northern Alberta Osteoporosis Program, Alberta Health Service, Edmonton, AB, Canada.

Lancet (London, England)
|September 14, 2025
PubMed
概括
此摘要是机器生成的。

骨质疏松性骨折是老年人群的主要健康问题. 本研讨会提供了关于骨质疏松症查,风险评估和有效治疗,包括安全药物管理的最新临床指导.

更多相关视频

Estrogen-Like Effect of Bazi Bushen Capsule in Ovariectomized Rats
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相关实验视频

Last Updated: Jan 17, 2026

Author Spotlight: Integrating Traditional Chinese Medicine with Modern Pharmacology and Genomics for Assessing Postmenopausal Osteoporosis in Mice
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科学领域:

  • 老年学
  • 整形医学
  • 药理学

背景情况:

  • 骨质疏松性骨折对老年人的健康造成重大负担.
  • 尽管有治疗方法, 骨质疏松症的治疗方法仍未得到充分利用.
  • 需要更新的临床方法来应对这一挑战.

研究的目的:

  • 为临床医生提供一种基于证据的骨质疏松症咨询方法.
  • 为治疗骨质疏松症和预防骨折提供实用指导.
  • 巩固现有证据和专家意见,以实践临床应用.

主要方法:

  • 对骨质疏松症管理发表的证据的审查.
  • 合作的专家意见综合.
  • 关注最新的查,风险评估和治疗干预措施.

主要成果:

  • 对查和骨折风险评估的新证据进行讨论.
  • 关于干预决定的指导,包括营养和药物治疗.
  • 用于治疗复杂患者群体和管理治疗中止的实用策略.

结论:

  • 一种最新的,基于证据的方法可以优化骨质疏松症的治疗.
  • 有效的查,风险评估和量身定制的治疗对于预防骨折至关重要.
  • 安全的治疗策略,包括停药,对于患者的安全至关重要.