职业和环境动物暴露与上呼吸道微生物组的改变有关
Beatrice Cornu Hewitt1, Mari-Lee Odendaal2, Myrna M T de Rooij1
1Institute for Risk Assessment Sciences (IRAS), Utrecht University, Utrecht, the Netherlands.
在畜牧场的职业接触显著改变了农民的上呼吸道 (URT) 微生物群. 环境暴露对呼吸道微生物组合产生了更微妙的影响.
科学领域:
- 微生物学 微生物学
- 环境健康 环境健康
- 职业健康 职业健康 职业健康
背景情况:
- 畜牧场的排放与呼吸系统健康问题有关.
- 呼吸道微生物组的变化可能会调解这些效应.
- 了解牲畜暴露对呼吸道微生物群的影响至关重要.
研究的目的:
- 研究职业和环境畜牧场暴露与上呼吸道 (URT) 微生物组之间的关联.
- 将山羊养殖者与农村居民的呼吸道微生物组进行比较.
- 评估环境畜牧暴露对农村居民微生物群的影响.
主要方法:
- 从山羊养殖者和农村居民那里收集鼻 (NP) 和口 (OP) 抽样.
- 使用16S rRNA基因片序列的微生物社区组成分析.
- 根据居民的牲畜密度和排放,评估农民的职业暴露和环境暴露.
主要成果:
- 与居民相比,山羊养殖者显示了较高的NP微生物多样性,但较低的OP多样性.
- 在农民的URT微生物组中发生了特定的细菌属 (Sphingomonas,Pseudomonas,Jeotgalicoccus,Rothia) 的变化.
- 居民的环境牲畜暴露与整体微生物群多样性无关,但在NP微生物群中显示出微妙的分类学变化.
结论:
- 在畜牧场的职业接触对URT微生物群有明显的影响.
- 畜牧场的环境暴露对URT微生物群有更微妙的影响.
- 这些微生物组变化可能会对牲畜暴露的个体的呼吸系统健康产生影响.
更多相关视频
09:01The Bovine Lung in Biomedical Research: Visually Guided Bronchoscopy, Intrabronchial Inoculation and In Vivo Sampling Techniques
Published on: July 3, 2014
05:31Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels
Published on: August 7, 2017
相关概念视频
Common Respiratory Disorders
Upper respiratory disorders impact the airways above the vocal cords, encompassing areas like the nose, sinuses, and throat. Various conditions fall under this category, including the common cold and allergic rhinitis. These disorders can stem from several causes,...
Asthma-I: Introduction
Anatomy of Respiratory System I: Upper Respiratory Tract
Nose and nasal cavity
The nose and nasal cavity represent the main external openings of the respiratory tract....
Chronic Obstructive Pulmonary Disease-II: Pathophysiology
Chronic Inflammation
Drugs Used in Upper Respiratory Disorders: Overview
Antihistamines (e.g., Benadryl) block histamines from binding. Histamines are chemicals released during an allergic reaction in the body. As a...
Types of Toxins
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...
