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Updated: Jan 17, 2026

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准TDP-43激活的GRP78/内质网膜应激轴抑制三阴性乳腺癌的进展

Jiao Wang1, Haotian Xu1, Li Tang1

  • 1Department of Pathophysiology, Chongqing Medical University, Chongqing, China.

Biochemical pharmacology
|September 14, 2025
PubMed
概括

TAR DNA结合蛋白-43 (TDP-43) 通过增加内质网膜 (ER) 压力,促进三阴性乳腺癌 (TNBC) 的生长. 抑制TDP-43可以减少癌细胞的增殖和迁移,为TNBC提供潜在的治疗点.

关键词:
细胞迁移 细胞迁移细胞的增殖细胞的增殖.压力ERER压力ERER压力在 GRP78 中使用.在TDP-43中使用.美国TNBC电视台

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