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Updated: Jan 17, 2026

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对IMP2二分化和RNA结合的结构见解

Stephen A Zorc1, Paola Munoz-Tello2, Timothy O'Leary3

  • 1Department of Molecular Medicine, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, Jupiter, FL, USA; The Skaggs Graduate School of Chemical and Biological Science, The Scripps Research Institute, La Jolla, CA, USA.

Journal of structural biology
|September 14, 2025
PubMed
概括

胰岛素样生长因子2的mRNA结合蛋白2 (IGF2BP2) 主要形成二次体,RNA结合改变其结构. 了解IGF2BP2的完整结构是针对癌症和代谢疾病的药物发现的关键.

关键词:
在HDX-MS中使用HDX-MS.在IGF2BP2BP2中使用.在 IMP2 中,MP2 包含了 IMP2.RNA结合蛋白 (RBP) 是一种RNA结合蛋白.萨克斯 (SAXS) 的时间

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