内分泌和外科手术专业之间的α阻塞实践的差异,用于发红细胞瘤和帕拉甘瘤切除:一个单一中心的回顾性研究
Jorge E Mosquera1, Shubham Agarwal1, Megan Maxwell2
1Division of Endocrinology, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas.
概括
在内分泌和外科手术组之间,色细胞瘤和状细胞瘤手术的术前α阻塞策略有所不同,但术后结果相似. 瘤大小和患者年龄影响了手术期间的血液动力学变异性.
科学领域:
- 内分泌学 在内分泌学.
- 手术瘤学手术瘤学
- 心血管生理学心血管生理学
背景情况:
- 外科手术是对染细胞瘤和偏角细胞瘤的最终治疗方法.
- 手术前的阿尔法阻塞实践各不相同,它们对治疗结果的影响尚不清楚.
研究的目的:
- 为了比较内分泌和外科专业之间的手术前的α阻塞策略.
- 评估这些策略对外科手术期间血液动力学结果的影响.
主要方法:
- 在78名经受染细胞瘤/副瘤切除 (2006-2023) 的患者进行了回顾性纵向队列研究.
- 在内分泌 (n=28) 和手术 (n=50) 组之间对α阻塞持续时间,剂量和频率进行比较.
- 对外科手术期间血液动力学参数的分析.
主要成果:
- 基线荷尔蒙概况或瘤大小没有显著差异.
- 内分泌组使用了更短的阻塞持续时间,但剂量和频率更高.
- 经手术后的血液动力学结果在各组之间是可比的.
- 更大的瘤大小和更高的甲基氨酸水平与低血压相关.
- 升高的甲氨酸和年龄较大与长时间的高血压相关.
结论:
- 阿尔法阻塞策略的差异没有影响外科手术期间的血液动力学结果,这表明管理灵活性.
- 瘤负担和患者年龄是影响血液动力学变异性的关键因素.
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