探索促炎饮食和生活方式与认知功能之间的相关性:莫利-萨尼研究的横截面结果
Francesca Bracone1, Alessandro Gialluisi2, Marialaura Bonaccio1
1Unit of Epidemiology and Prevention, IRCCS Neuromed, Pozzilli, Italy.
Journal of affective disorders
|September 14, 2025
概括
促炎症饮食与意大利成年人的认知能力下降有关,特别是与抑郁症结合时. 基于营养的预防是认知健康的关键.
科学领域:
- 营养与公共卫生 营养与公共卫生
- 神经科学是一个神经科学.
- 老年学是一门学科.
背景情况:
- 慢性低度炎症是对认知能力下降的日益关注的问题.
- 调查导致炎症和认知功能的饮食和生活方式因素至关重要.
研究的目的:
- 探索促炎饮食和生活方式模式与意大利成年人的认知功能之间的关联.
- 评估饮食炎症评分 (DIS) 和生活方式炎症评分 (LIS) 对认知状态的影响.
主要方法:
- 利用饮食炎症评分 (DIS) 和生活方式炎症评分 (LIS) 来量化炎症潜力.
- 在2474名意大利成年人中使用蒙特利尔认知评估 (MoCA) 测试评估认知功能.
- 采用多项多变量物流分析,调整炎症生物标志物和抑郁症状 (PHQ-9).
主要成果:
- 较高的DIS和LIS与认知能力下降的几率增加有关 (MoCA ≤18).
- 在中度至重度抑郁症状 (PHQ-9 ≥10) 的个体中,DIS与认知衰退之间的关联显著更强.
- 与饮食因素 (DIS) 相比,生活方式因素 (LIS) 与认知衰退的关联较弱.
结论:
- 饮食中高的炎症潜力是意大利成年人认知能力下降的重要因素.
- 促炎症饮食和抑郁症状的结合加剧了认知障碍的风险.
- 强调了以营养为重点的初级预防策略对认知健康的重要性,特别是对于那些患有抑郁症的人来说.
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