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Updated: Jan 17, 2026

Parallel Interrogation of β-Arrestin2 Recruitment for Ligand Screening on a GPCR-Wide Scale using PRESTO-Tango Assay
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在GPCR偏差信号和连接物药理学的未来方向

Dannya Estau1, Zijian Li2,3

  • 1Department of Cardiology and Institute of Vascular Medicine, Peking University Third Hospital; Beijing Key Laboratory of Cardiovascular Receptors Research, State Key Laboratory of Vascular Homeostasis and Remodeling, and NHC Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides, Peking University; Research Unit of Medical Science Research Management/Basic and Clinical Research of Metabolic Cardiovascular Diseases, Chinese Academy of Medical Sciences, Peking University, Beijing, China.

Handbook of experimental pharmacology
|September 14, 2025
PubMed
概括

G蛋白结合受体 (GPCR) 偏向信号传递促进了对受体生物学和药物开发的理解. 未来的研究方向集中在理论,结构,方法和连接体药理学上,以获得更安全,更有效的GPCR向治疗.

关键词:
有偏差的信号传输.未来的方向 未来的方向G蛋白结合受体的受体是G蛋白结合受体的受体.连接物药理学 连接物药理学

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