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嵌合式抗原受体T细胞疗法的现状及其耗尽机制

Huiwen Zhang1,2, Juwei Gao1,2, Zipeng Zhang2

  • 1School of Pharmacy, Shandong Second Medical University, Weifang, Shandong, P.R. China.

Immunotherapy
|September 15, 2025
PubMed
概括

化学抗原受体 (CAR) T细胞疗法在瘤学方面表现有前途,但患有T细胞枯竭. 了解和抑制CAR-T细胞功能障碍对于提高抗瘤疗效和持续性至关重要.

关键词:
卡特-T细胞的耗尽化学抗原受体 T 细胞采用细胞疗法采用细胞疗法癌症免疫疗法免疫疗法瘤免疫的微环境

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