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Updated: Jan 17, 2026

Quantitative Structure-Activity Relationship, Activity Prediction, and Molecular Dynamics of Non-nucleotide Reverse Transcriptase Inhibitors
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增强 thiazolide 疗效:C-4 基修饰驱动了选择性的 SARS-CoV-2 抑制

Rizwan Bashir1, Sobia Jabeen1, Wasim Abbas1

  • 1Health Biotechnology Division, National Institute for Biotechnology and Genetic Engineering, Pakistan Institute of Engineering and Applied Sciences (NIBGE-C, PIEAS), Faisalabad, Pakistan.

Future medicinal chemistry
|September 15, 2025
PubMed
概括

研究人员开发了新的 thiazolide 类似物来对抗 SARS-CoV-2,改进了 nitazoxanide (NTZ). 一些类似物显示显著增强抗病毒功效和选择性,为新的广泛抗病毒疗法提供了有前途的线索.

关键词:
这就是SARS-CoV-2病毒.铁酸化物 铁酸化物班佐提亚化物 班佐提亚化物广泛的抗病毒药物.尼塔佐化物类似物

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