阿多拉1通过Irf1-PD-L1信号轴促进结肠癌的免疫逃避

Yubin Wang1, Yilin Zeng1, Peizhong Chen1

  • 1Department of Gastroenterology, Quanzhou First Hospital Affiliated to Fujian Medical University Quanzhou 362000, Fujian, China.

PubMed
概括

向腺A1受体 (Adora1) 可以抑制结肠癌中的免疫逃避. 降低Adora1的调节抑制了编程死亡配体1 (PD-L1) 的表达,减少T细胞疲劳和瘤生长.

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