在中国多病症患者中评估药物素养及其决定因素
Xinyi Li1,2, Changcheng Shi2,3, Lihong Liu1
1Department of Pharmacy, China-Japan Friendship Hospital, Beijing, People's Republic of China.
Patient preference and adherence
|September 15, 2025
概括
患有多种慢性疾病 (多种疾病) 的患者往往具有较低的药物素养. 干预措施应侧重于提高理解力,特别是对于老年人,受教育程度较低和农村人士,同时应对抑郁症和社会支持.
科学领域:
- 医疗保健服务研究 医疗服务研究
- 患者教育 患者教育
- 老年学是指老年学的学科.
背景情况:
- 多病症,即多种慢性疾病的存在,在管理患者护理方面提出了重大挑战.
- 有效的药物管理对于多病症患者至关重要,以预防不良事件并改善健康结果.
- 药物素养,即个人能够获得,处理和理解必要的基本健康信息和服务以做出适当的健康决策的程度,是药物坚持和自我管理的关键决定因素.
研究的目的:
- 调查多病症患者中药物素养的现状.
- 确定影响该人口药物素养的关键因素.
主要方法:
- 进行了一项横截面调查,涉及3,955名被诊断患有多病症的患者.
- 该研究使用药物识字量表进行评估,数据收集于2023年6月至8月之间.
- 统计分析包括威尔科克森测试,克鲁斯卡尔-瓦利斯测试,皮尔森相关性和多重阶段线性回归.
主要成果:
- 平均药物素养得分为18.56±4.52 (尺度范围:6-30).
- 与更高的药物素养积极相关的因素包括年龄较小,高等教育水平,目前已婚,未婚或离婚,城市居住和更大的社会支持.
- 相反,年龄较大 (≥60岁),教育程度较低,寡妇身份,居住在中国中部/西部,抑郁症状得分较高与药物素养较低有关.
结论:
- 药物素养是多病症患者的关键问题.
- 干预措施的目的应该是提高对药物的理解,特别是对于弱势子组,如老年人,低教育程度的人以及居住在农村或特定地理区域的个人.
- 解决抑郁症和加强社会支持是改善多病症患者药物素养和管理的重要组成部分.
相关概念视频
01:21Health Literacy
5.2K
Health literacy is an individual's or a community's capacity to comprehend, receive, read, and use relevant healthcare information and services. The World Health Organization (WHO, 2018) defines health literacy as the cognitive and social skills that determine the ability of individuals to gain access to, understand, and use information in ways that promote and maintain good health. As a result, the WHO helps individuals manage long-term health concerns, participate in preventative...
5.2K
01:15Drug Dosing: Geriatric Patients
228
Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
228
01:08Effect of Hepatic Disease on Pharmacokinetics: Dose Adjustments Due to Hepatic Impairment
257
Hepatic impairment, characterized by decreased liver function, does not uniformly mandate adjustments in drug dosage. Whether dosage modifications are necessary depends on various factors related to the drug's metabolism and elimination pathways. If a drug is primarily excreted via the kidneys and bypasses significant hepatic processing, if it undergoes minimal metabolic transformation in the liver, or if it is volatile and primarily expelled through the lungs, dose adjustments may not be...
257
01:21Drug Dosing: Obese Patients
225
In the United States, obesity is a prominent concern. It is linked to heightened mortality rates due to increased occurrences of conditions such as hypertension, atherosclerosis, coronary artery disease, and diabetes compared to nonobese individuals. A patient is classified as obese if their actual body weight surpasses the ideal or desirable body weight by 20%, based on Metropolitan Life Insurance Company data. Ideal body weights consider average weights and heights for males and females...
225
01:18Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism
197
Geriatric patients show significant variation in how their bodies process medications, which can change how effective and safe treatments are. The liver is the primary organ where drug metabolism occurs, involving two main types of chemical reactions: phase I and II. Phase I metabolism is driven by the cytochrome P450 enzyme system, which includes key types such as CYP3A, CYP2D6, and CYP2C9. Research indicates that while aging doesn't notably alter the levels or activity of these enzymes, it...
197
01:28Drug Therapy
245
The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
Antianxiety Medications
245