手术前的表现状况与老年患者患有耐火性性结肠炎的术后致命并发症有关
Yuki Horio1, Motoi Uchino2, Yusuke Tomoo2
1Department of Gastroenterological Surgery, Hyogo Medical University, Nishinomiya 663-8501, Hyogo, Japan. yu-horio@hyo-med.ac.jp.
World journal of gastrointestinal surgery
|September 15, 2025
概括
老年性结肠炎患者面临致命并发症的高风险,特别是肺炎. 低体重指数和不良表现状态是关键预测因素,这表明在衰弱之前,早期手术至关重要.
科学领域:
- 胃肠病学 胃肠病学
- 手术瘤学手术瘤学
- 老年医学 老年医学
背景情况:
- 老年患者的耐火性性结肠炎 (UC) 预后不佳,需要及时的手术干预.
- 生物疗法的日益复杂化使UC患者的手术时间变得复杂.
- 对于老年UC患者的手术转换缺乏明确的标准.
研究的目的:
- 确定耐火性性结肠炎 (UC) 的老年患者术后并发症的危险因素.
主要方法:
- 对191名耐火性UC的老年患者 (≥60岁) 进行了回顾性分析,这些患者接受了切除术.
- 在2012年4月至2024年3月期间,从兵庫医科大学收集的数据.
- 主要结局:确定致命的术后并发症的危险因素.
主要成果:
- 致命并发症的发生率为9.4% (18/191),肺炎是最常见的.
- 致命并发症的独立风险因素包括低体重指数 (BMI) <17 kg/m2 (OR=4.08) 和ECOG性能状态 (ECOG-PS) ≥3 (OR=14.5).
结论:
- 低BMI和ECOG-PS得分是老年UC患者致命并发症的重要危险因素.
- 在患者出现显著体重减轻或移动性问题之前,建议立即进行手术.
- 早期的手术决策可以减轻衰弱的老年UC患者的风险.
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