门腺癌与门周边帕杰特病:一个病例报告
Sheng-Wei Wu1, Yao Rong1, Gui-Jin Chen1
1Department of General Surgery, General Hospital of Southern Theater Command, Guangzhou 510000, Guangdong Province, China.
World journal of gastrointestinal surgery
|September 15, 2025
概括
门腺癌与二次围帕杰特病 (PPD) 是罕见的,并且经常被误诊. 通过结肠镜检查和活检进行早期诊断,然后进行腹膜关节切除 (APR),可以改善这种具有挑战性的疾病的结果.
科学领域:
- 胃肠病学 胃肠病学
- 手术瘤学手术瘤学
- 皮肤病学 皮肤病学
背景情况:
- 门腺癌与二次周帕杰特病 (PPD) 是一种罕见的疾病.
- 它经常表现为异型症状,导致误诊为良性疾病,如或湿疹.
- 延迟诊断显著影响治疗和预后.
研究的目的:
- 总结道腺癌与二次性PPD的关键诊断和治疗点.
- 突出错误诊断的原因,并提高临床意识.
- 提出有效的治疗策略,并强调后续行动.
主要方法:
- 一个72岁的女性患者的回顾性分析,在2年内出现了近症状.
- 通过结肠镜检查,围皮肤活检和免疫组织化学染色 (CK7,CK20) 证实了诊断.
- 治疗涉及3D腹腔镜辅助腹切除 (APR) 与延长的围皮肤切除.
主要成果:
- 这位患者最初被误诊为.
- 通过活检和免疫组织化学检查获得了确定的诊断.
- 患者在APR后实现了负边缘和初级伤口愈合,在12个月的随访中没有复发或转移.
结论:
- 二次性PPD的误诊率很高,需要对老年患者具有持续的围症状的临床怀疑.
- 及时进行结肠镜检查和免疫组织化学测试对于准确诊断至关重要.
- 延长围切除的APR是一种有效的治疗方法,标准化的长期随访对预后至关重要.
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