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膜性狭窄性疾病的内镜口腔尿路造术

Garrett N Ungerer¹, Sierra T Pence¹, Bridget L Findlay¹

¹Department of Urology, Mayo Clinic, Rochester, MN, USA.

Translational andrology and urology

|September 15, 2025

概括

内镜口腔粘膜尿道整形 (EBMGU) 有效地治疗具有挑战性的膜性尿道狭窄,特别是在先前接受放射治疗的患者中. 这种重建性手术显示出有希望的短期成功率,并有助于随后的人工泌尿关节的放置.

科学领域:

泌尿器科泌尿器科泌尿器科泌尿器科
重建性手术是一种重建性手术.
尿道收窄管理尿道收窄管理

背景情况:

膜性尿道狭窄由于其位置和对尿失禁的影响而存在重大重建挑战.
管理是复杂的,特别是在先前有辐射或消灭性狭窄的患者中.

研究的目的:

评估膜性狭窄性疾病内镜口腔粘膜尿道成形术 (EBMGU) 的手术技术,结果和并发症.
评估EBMGU在患者之前的辐射和消灭性狭窄的疗效.

主要方法:

在2022年2月至2024年12月期间接受EBMGU治疗的28名男性患者的回顾性评估.
纳入标准:膜性收缩性疾病,至少4个月的随访囊镜检查,包括消灭性收缩和辐射后病例.
收集的数据:人口统计,先前的治疗,尿流,PVR,狭窄细节,手术数据,并发症. 手术成功被定义为在4个月后通过17-Fr囊镜.

主要成果:

平均年龄为71岁,平均随访时间为8个月. 85%的患者先前接受过放射治疗,17%的患者患有消灭性狭窄,93%的患者先前接受过干预.
在4个月的囊镜术中,整体成功率为82%,所有患有骨盆骨折尿道损伤 (PFUI) 的患者都是专利.
57%的患者进行了人造泌尿道 (AUS) 放置;10%的患者由于严重并发症需要进行尿路转移的囊切除术.

结论:

EBMGU是一种有效的短期选择,用于管理膜性狭窄性疾病,特别是在放射患者中.
这种手术的成功率很高,并且在大多数患者中促进了随后的人工泌尿关节的安置.
虽然有效,但需要囊切除术的严重并发症可能发生在一小部分患有广泛辐射损伤的患者中.

关键词:

尿路形术是指进行尿路形术.口粘膜移植口粘膜移植进行内镜检查.尿道狭窄尿道狭窄

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