患有下泌尿道症状 (LUTS) 的男性与勃起功能障碍相关的因素:一个下泌尿道功能障碍研究网络 (LURN) 研究的症状
Devin Boehm1, Abigail R Smith1, Sarah A Mansfield2
1Northwestern University, Feinberg School of Medicine, Chicago, IL, USA.
Translational andrology and urology
|September 15, 2025
概括
勃起功能障碍 (ED) 与尿失禁,焦虑和糖尿病有关,男性有下泌尿道症状 (LUTS). 解决这些可修改的因素可能会改善勃起功能和自信.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 安德罗学与人类学
- 男人的健康 男人的健康
背景情况:
- 勃起功能 (EF) 和其与下泌尿道症状 (LUTS) 和并发症的关系在大型患者队列中仍未得到充分研究.
- 这项研究调查了在寻求LUTS治疗的男性中尿路症状,并发症和勃起功能障碍 (ED) 之间的关联.
研究的目的:
- 在447名寻求治疗的男性中确定LUTS,并发症和ED之间的关系.
- 在这个人群中确定与勃起功能障碍和低勃起自信相关的因素.
主要方法:
- 来自下尿道功能障碍症状研究网络 (LURN) 观察队列研究的数据分析.
- 多变量后勤回归模型被用来量化LUTS和ED之间的关系,包括焦虑,抑郁,肥胖,心血管疾病 (CVD) 和糖尿病等共变量.
主要成果:
- 与非性活跃男性相比,性活跃男性年轻,糖尿病和心血管疾病的发病率较低.
- 在性活跃的男性中,ED与糖尿病 (OR=2.4),老年 (OR=1.4每5年),尿失禁 (OR=1.2) 和焦虑 (OR=1.4每10个T分数单位) 相关.
- 性活跃男性的低勃起自信与焦虑 (OR=1.6),老年 (OR=1.3),使用PDE5抑制剂 (OR=2.1) 和糖尿病 (OR=2.2) 有关.
结论:
- 尿失禁 (UI) 和ED之间的联系表明,在UI的男性中,对ED进行例行查.
- 焦虑和糖尿病是与ED和LUTS男性的勃起自信降低相关的可改变因素.
- 这些发现强调了一种整体治疗LUTS男性的方法的重要性,同时考虑尿路和性健康.
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