巴西亚马逊地区儿童和青少年的癌症:基于人口的研究
Isabella Pereira Gadelha1,2, Fernanda Cristina Rosa Alves1,2, Samara Machado Castilho1
1Belém Population-Based Cancer Registry, Belém 66093-677, Brazil.
Ecancermedicalscience
|September 15, 2025
概括
在贝莱姆和阿纳尼德瓦的儿童癌症发病率显示白血病是最常见的诊断. 数据突出显示男性患病率较高,生命状况信息有限,影响了对恶性瘤的监测.
科学领域:
- 流行病学 流行病学
- 儿科瘤学 儿科瘤学
- 公共卫生 公共卫生
背景情况:
- 儿童癌症每年影响全球约40万名儿童,发展中国家的负担很大.
- 到2023年,巴西预计将有7900例儿童癌症病例,将癌症定位为该人口中主要的死亡原因.
- 了解儿童和青少年的癌症流行病学对于加强健康监测和干预策略至关重要.
研究的目的:
- 在贝莱姆和阿纳尼德瓦的0-19岁个体中划分癌症的发病率和死亡率模式.
- 提供特定地区儿童和青少年恶性瘤的详细流行病学概况.
主要方法:
- 一项量化,描述性的研究利用了基于人口的癌症注册表 (RCBP) 的数据.
- 分析包括2010-2019年贝莱姆和Ananindeua0-19岁居民的癌症发病率和死亡率.
- 检查的变量:年龄,性别,种族,形态和病例结果. 发病率计算为 (新病例/总人口) ×100,000.
主要成果:
- 在0-19岁的年龄组中,共记录了846例恶性瘤的新病例.
- 白血病是最常见的形态 (42.31/100,000),其次是中枢神经系统瘤 (17.92/100,000),淋巴瘤 (15.82/100,000) 和骨瘤 (12.27/100,000).
- 男性的发病率更高,15-19岁的年龄组出现了最多的病例. 很大一部分 (66.1%) 缺乏重要状态信息,其中29.6%的确诊死亡.
结论:
- 这项研究提供了关于贝莱姆和阿纳尼德瓦的儿童和青少年恶性瘤的重要流行病学数据.
- 报告指出,从RCBP系统获取数据存在挑战,可能会影响综合分析.
- 建议进一步改进数据收集,以加强癌症监测并为公共卫生战略提供信息.
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