前十字带重建时的年龄增加与代谢综合征之间的关联
Anthony Mantor1, Sonu Bae1, Michael Burton2
1Jameson Crane Sports Medicine Institute, College of Medicine, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Orthopaedic journal of sports medicine
|September 15, 2025
概括
前十字带重建 (ACLR) 的年龄与代谢综合征 (MetSy) 患病率无关. 然而,接受ACLR治疗的老年患者表现出更高的HbA1c和禁食葡萄糖水平,表明潜在的代谢变化.
科学领域:
- 整形外科手术 整形外科手术
- 代谢健康 代谢健康
- 流行病学 流行病学
背景情况:
- 代谢综合征 (MetSy) 是一个日益严重的全球健康问题,患病率随着年龄的增长而增加.
- 前十字带重建 (ACLR) 时的年龄与MetSy患病率之间的关系仍然未被探索.
研究的目的:
- 调查接受ACLR治疗的患者年龄与MetSy患病率之间的关联.
主要方法:
- 一项队列研究包括493名接受ACLR治疗的成年患者,其中包括BMI,甘油三,高血糖,血压和HbA1c的数据.
- MetSy是根据既定的标准定义的 (5个因素中的≥3:高BMI,甘油三,低HDL,高血压或高葡萄糖).
- 根据ACLR的年龄分组患者:18-29岁,30-39岁,40-49岁和≥50岁.
主要成果:
- 整体MetSy患病率为38.5%,并且在各年龄组之间没有显著差异 (P = .70).
- 个别的MetSy成分 (BMI,甘油三,高血糖,血压) 没有显示出与年龄相关的显著差异.
- 然而,年龄≥50岁的患者与年轻组相比,估计的禁食葡萄糖 (P < .01) 和HbA1c (P < .01) 显著更高.
结论:
- 在ACLR中,晚年并不与代谢综合征的更高患病率有关.
- 升高的HbA1c和空腹葡萄糖水平可能与ACLR发生时的年龄有关.
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