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Updated: Jan 17, 2026

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NF-κB2突变对Tfh细胞分化的影响及其在免疫功能中的关键作用

Yao Chen1, Weitao Zhou2, Leying Li1

  • 1Department of Pulmonary Medicine, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China.

Translational pediatrics
|September 15, 2025
PubMed
概括

NF-κB2突变通过破坏T毛囊辅助细胞 (Tfh) 细胞分化来损害免疫功能. 一个特定的突变阻碍p100处理,减少Tfh细胞并影响免疫反应.

关键词:
在 NF-κB2 中.毛囊T辅助细胞 (Tfh细胞)常见的可变免疫缺陷 (CVID)基因突变是一种基因突变.免疫缺陷是一种免疫缺陷.

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