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Updated: Jan 17, 2026

3D Multicolor DNA FISH Tool to Study Nuclear Architecture in Human Primary Cells
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重建尼安德特人的3D基因组组织揭示了染色质折叠形成的表型和序列分歧

Evonne McArthur1,2,3, David C Rinker4, Yang Cheng5

  • 1Department of Medicine, University of Washington, Seattle, WA.

bioRxiv : the preprint server for biology
|September 15, 2025
PubMed
概括

我们使用深度学习来重建古人类的3D基因组折叠,揭示了与人类进化相关的基因调节差异. 这种3D基因组结构影响了古老的侵入现代人类.

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