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Updated: Jan 17, 2026

Ultra-long Read Sequencing for Whole Genomic DNA Analysis
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Published on: March 15, 2019

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混合长度基因组测序 (blend-seq):将短读数与低覆盖长读数相结合,以最大限度地发现变异

Ricky Magner1, Fabio Cunial1, Sumit Basu2

  • 1Broad Institute of Harvard and MIT, Cambridge, MA, USA.

bioRxiv : the preprint server for biology
|September 15, 2025
PubMed
概括

混合测序 (Blend-seq) 结合了短读和低覆盖长读测序数据,以提高单个样本的变异发现和分阶段. 这种具有成本效益的工作流改善了单核酸多态性和结构变异检测,单独优于高覆盖率的短读.

关键词:
优化成本,优化成本.基因型定制是基因型定制.很难绘制地图的地区.混合测序是指混合测序.长时间阅读序列排序.阶段化分阶段化.简读序列的短阅读序列.小型变体的小变体结构变体 结构变体

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