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Updated: Jan 17, 2026

A Murine Cell Line Based Model of Chronic CDK9 Inhibition to Study Widespread Non-Genetic Transcriptional Elongation Defects TEdeff in Cancers
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瘤抑制剂CYLD作为mTOR的二维基因酶,限制其活动

Stephanie A Fernandes1,2, Jiyoung Pan1,2, Diana S Terziyska1

  • 1Max Planck Institute for Biology of Ageing (MPI-AGE), 50931 Cologne, Germany.

bioRxiv : the preprint server for biology
|September 15, 2025
PubMed
概括

瘤抑制剂CYLD二维基因酶 (DUB) 通过去除泛基因链,直接调节mTORC1/2的活动. CYLD的失活导致mTOR过活化,影响细胞生长和存活,并与CYLD皮肤综合征有关.

关键词:
这就是CYLDLD.在这里,dub,dub,dub是什么意思.年龄化的老龄化.细胞生长细胞的生长.圆柱体romatosis 的情况.在mTOROR中使用mTOR.无处不在的化

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