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Updated: Jun 26, 2026

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缺少IRF8会以性别依赖的方式导致类似焦虑的行为

Stella Zhu1, Keita Saeki1, Rose-Marie Karlsson2

  • 1Section on Molecular Genetics of Immunity, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.

bioRxiv : the preprint server for biology
|September 15, 2025
PubMed
概括

微质中的转录因子IRF8以性别依赖的方式控制焦虑. 雌性IRF8淘汰赛小鼠表现出增加的焦虑,与胎儿阶段的氧化还原失调和更高反应性氧物种 (ROS) 生产有关.

关键词:
在 IRF8 中,我们可以使用 IRF8.类似焦虑的行为.微质细胞中的微质细胞强迫症是一种强迫症.有活性氧物种的反应性氧物种.

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