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对左心室全球纵向应变改善的评估,经过过导管大动脉置换后的评估

Jad Kassem¹, Rachad Ghazal², Omar Fakhreddin³

¹Department of Radiology, Mount Sinai West, New York, NY, USA.

Journal of cardiovascular echography

|September 15, 2025

概括

透气管大动脉置换 (TAVR) 显著改善左心室全球纵向应变 (GLS) 术后一年. 在GLS中这种增强表明,在TAVR治疗严重的大动脉狭窄后,左心室机械和整体心脏功能得到了改善.

科学领域:

心脏病学心脏病学
心脏外科手术心脏外科手术
医疗成像医学成像

背景情况:

过导管大动脉置换 (TAVR) 是严重症状大动脉狭窄症 (AS) 的首要治疗方法.
新出现的证据表明,TAVR可能会改善左心室 (LV) 功能,而不仅仅是缓解AS.
左心室全球纵向应变 (GLS) 是心肌功能的一个敏感标志物.

研究的目的:

为了评估TAVR后LV全球纵向应变 (GLS) 的变化.
确定GLS是否可以作为TAVR后改善LV力学的亚临床指标.
探索基线参数与GLS改进之间的相关性.

主要方法:

对80名患有严重AS且接受TAVR的患者进行了回顾性分析.
基线和1年TAVR后心声回声学参数的比较.
计算LV GLS以评估功能变化.

主要成果:

在TAVR后一年,LV GLS显著改善,从-16.8%到-19.2% (P < 0.001).
观察到腹腔间隔膜直径和LV质量指数的显著减少.
左心室喷射分数 (LVEF) 略有改善 (59.2%至62.1%,P <0.01).

结论:

TAVR导致LV GLS的显著改善,表明LV性能得到改善.
在TAVR后GLS改善的程度与基线LV质量指数和缩功能相关.
GLS是评估TAVR对LV力学影响的有价值的亚临床标记.

关键词:

大动脉狭窄症大动脉狭窄症主动脉植入装置的动脉.全球纵向菌株全球纵向菌株压力成像检测压力成像检测通过导管更换大动脉门.

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