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Updated: Jan 17, 2026

Yeast As a Chassis for Developing Functional Assays to Study Human P53
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Published on: August 4, 2019

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与Li-Fraumeni综合征相关的p53变体破坏脏和尿路发育

Adrian Romero, Alejandra Davilavaladez, Alexandria T M Blackburn

    medRxiv : the preprint server for health sciences
    |September 15, 2025
    PubMed
    概括

    在Li-Fraumeni综合征中,致病性TP53变异可能导致脏和尿路的先天性异常 (CAKUT) 和生殖器缺陷 (GD). 这揭示了p53在泌尿器官发育中的新发展作用.

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