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相关概念视频

Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

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Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
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相关实验视频

Updated: Jan 17, 2026

Standardized Data Acquisition for Neuromelanin-Sensitive Magnetic Resonance Imaging of the Substantia Nigra
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一个供应商中立的功能性MRI采集协议,用于多站点研究.

Jon-Fredrik Nielsen1,2, Maximillian K Egan1, Qingping Chen3

  • 1Functional MRI Laboratory, Department of Radiology, University of Michigan, Ann Arbor, USA.

medRxiv : the preprint server for health sciences
|September 15, 2025
PubMed
概括
此摘要是机器生成的。

这项研究引入了一个开放的,供应商中立的BOLD SMS-EPI协议,使用Pulseq进行多站点fMRI研究. 它确保了各供应商一致的实验条件,减少了功能性MRI数据的位置差异.

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科学领域:

  • 神经成像是一种神经成像.
  • 磁共振成像 (MRI) 是一种磁共振成像技术.
  • 生物医学工程 生物医学工程

背景情况:

  • 传统的MRI协议是特定于供应商的,这导致了多地点功能性MRI (fMRI) 研究中的不一致性.
  • 缺乏标准化阻碍了神经成像研究中的可复制性和跨站点比较.
  • 现有的供应商特定管道充当"黑子",限制透明度和定制性.

研究的目的:

  • 提出一个开放的,供应商中立的BOLD SMS-EPI协议,以取代当前的供应商特定管道.
  • 确保在不同MRI扫描仪供应商之间具有相同的SMS-EPI脉冲序列和图像重建.
  • 为多个地点的fMRI研究建立已知和一致的实验条件.

主要方法:

  • 开发基于Pulseq框架的供应商中立的BOLD SMS-EPI协议.
  • 在各供应商之间实施相同的SMS-EPI脉冲序列和图像重建.
  • 使用西门子和GE扫描仪上的健康志愿者的静止状态fMRI数据测试该协议.

主要成果:

  • 与特定供应商的协议相比,fMRI数据显示出较少的位点变异.
  • 在不同扫描仪供应商中确认了相同的SMS-EPI脉冲序列和图像重建.
  • 为研究人员提供实用资源,以整合Pulseq fMRI协议.

结论:

  • 开放的,供应商中立的Pulseq fMRI协议为多站点研究提供了标准化的解决方案.
  • 这种方法通过确保一致的实验条件来提高神经成像研究的可重现性.
  • 该协议作为未来开发新型MRI采集和重建方法的基础.