性发育障碍中的性别失调:在单一中心的方法和患病率
Lamia Inayath1, Shivaji Mane1, Hemangi Ramchandra Athawale1
1Department of Paediatric Surgery, Grant Government Medical College and Sir JJ Group of Hospitals, Mumbai, Maharashtra, India.
Journal of Indian Association of Pediatric Surgeons
|September 15, 2025
概括
这项研究分析了性发展障碍 (DSD) 的青少年和成人患者的性别失调 (GD) 患病率. 在5α-减少酶缺乏症中,GD最常见,在先天性上腺增生和完全雄激素不敏感综合征中最少.
科学领域:
- 内分泌学 在内分泌学.
- 精神病学是一个精神病学.
- 遗传学 是一个遗传学.
背景情况:
- 性别障碍症 (GD) 的特点是个人的性别认同与生物性别之间的不匹配.
- 性发育障碍 (DSD) 涵盖了一系列影响性特征发展的疾病.
研究的目的:
- 确定患有DSD的青少年和成年患者中GD的患病率.
- 描述DDS患者GD的治疗方法.
主要方法:
- 对10-19岁 (青少年) 和20岁以上 (成年) 的患有DSD的患者进行了回顾性研究,这些患者在2017-2024年期间接受了手术.
- 包括标准要求在手术干预之前进行详细的心理分析.
主要成果:
- 包括36名患者 (11-47岁),平均呈现年龄为18.9岁.
- 性别障碍症在患有5α-减少酶缺乏症的患者中最为普遍.
- 先天性上腺增生症和完全的雄激素不敏感综合征显示GD的患病率最低.
结论:
- 对于青少年DSD的手术干预是一个复杂和有争议的问题.
- 全面的心理社会支持对于患者的决策至关重要.
- 多学科的方法对于优化DSD患者的身体和心理结果至关重要.
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