持续的瞳孔膨胀和不可逆转的水病在HLA-B27相关的尿道炎
Hamdah M Alkhaldi1, Wael A Alsakran2, Moustafa S Magliyah1
1Medical Retina and Uveitis, King Khaled Eye Specialist Hospital, Riyadh, SAU.
Cureus
|September 15, 2025
概括
在前膜炎后持续的固定扩张瞳孔,特别是与人白细胞抗原B27 (HLA-B27) 相关,是罕见的. 这一案例突出了类似于Urrets-Zavalia的综合征,可能与前段缺血有关.
科学领域:
- 眼科医生 眼科 眼科
- 神经眼科神经眼科
背景情况:
- 持久的固定扩张瞳孔是前膜炎后的一个不常见的并发症.
- 这在患有人类白细胞抗原B27 (HLA-B27) 相关性脑膜炎的患者中尤其罕见.
- 乌雷茨-扎瓦利亚类综合征,涉及前段缺血,是提出的机制.
研究的目的:
- 描述一个在HLA-B27相关的前额膜炎之后持续的固定扩张瞳孔的病例.
- 在本次演讲中讨论Urrets-Zavalia-like综合征的潜在作用.
主要方法:
- 一个38岁的女性患者的病例报告.
- 详细的神经眼科评估.
- 眼科病史的综述,包括复发的前性脑膜炎和HLA-B27突变.
主要成果:
- 患者在双边出现持续扩张和固定瞳孔 (无动瞳孔).
- 这发生在前脑膜炎的急性发作后,用局部环醇治疗.
- 瞳孔扩张仍然存在,尽管停止了水滴和眼内压力和炎症的稳定.
结论:
- 持久的固定扩张瞳孔可以发生在与HLA-B27相关的脑膜炎中,这表明类似于Urrets-Zavalia综合征.
- 在这种情况下,前段缺血可能在心动瞳孔的发展中发挥作用.
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