在新生儿中过度生理黄和交换输血
Muhammad Arif1, Maria Himayat1, Hina Nasir1
1Pediatric Medicine, Northwest General Hospital and Research Centre, Peshawar, PAK.
Cureus
|September 15, 2025
概括
过度的新生儿黄需要交换输血发生在14.7%的病例中. 关键因素包括纯母乳养,低出生体重和早产,强调需要监测和早期干预.
科学领域:
- 新生儿科学 新生儿科学
- 儿科 儿科 儿科
- 公共卫生 公共卫生
背景情况:
- 新生儿黄,特别是非结合性高 bilirubinemia,是常见的,可以导致 bilirubin 诱导的神经功能障碍 (BIND).
- 虽然生理黄通常是良性的,但严重的病例可能需要光疗或交换输血.
- 这项研究调查了过度生理黄的发病率和危险因素,使新生儿需要交换输血.
研究的目的:
- 为了确定过度生理黄的发生率,需要在新生儿中进行交换输血.
- 确定与这种情况相关的促成因素.
- 为了告知管理策略,以减少重症新生儿高 bilirubinemia.
主要方法:
- 从2020年1月到2023年1月的医疗记录进行了回顾性病例系列分析.
- 纳入标准:患有生理性高 bilirubinemia (血清 bilirubin ≥17 mg/dL) 的新生儿接受了交换输血.
- 收集的数据:人口统计,临床症状,养做法,实验室发现;使用IBM SPSS统计数据进行分析.
主要成果:
- 在136名患有过度黄的新生儿中,20名 (14.7%) 需要交换输血.
- 发现的常见因素:纯母乳养 (76.2%),低出生体重 (23.8%) 和早产 (14.3%).
- 平均总血清白血素从26.52±7.7 mg/dL降至14.16±2.6 mg/dL. 交换输血后.
结论:
- 显著的是,有14.7%的患有过度生理黄的新生儿需要交换输血.
- 纯母乳养,低出生体重和早产是显著的贡献因素.
- 早期识别,密切监测和有针对性的干预措施对于管理新生儿黄和预防严重后果至关重要.
相关概念视频
Changes in Skin Color: Clinical Perspectives
3.3K
The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
3.3K
Rh Blood Group
2.8K
The Rhesus (Rh) antigen is crucial in determining blood groups and ensuring compatibility during blood transfusions.
2.8K
Blood Transfusion and Agglutination
14.0K
Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
14.0K
Transcytosis of IgG
4.1K
Transcytosis is the process in which molecules are internalized by endocytosis, transported across the cell, and released through exocytosis from the opposite end of the cell. Molecules such as insulin, immunoglobulins, and certain nutrients are transferred through the recycling endosomes by recycling and transcytosis.
IgG molecules from a mother undergo transcytosis starting around 13 weeks of gestation. The amount of IgG transferred and entering the fetal blood circulation increases with...
IgG molecules from a mother undergo transcytosis starting around 13 weeks of gestation. The amount of IgG transferred and entering the fetal blood circulation increases with...
4.1K
Blood Transfusion
2.1K
Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
2.1K
Fetal Circulation
2.6K
Fetal circulation is a unique system that facilitates the exchange of gases, nutrients, and waste products between the developing fetus and the mother. This intricate process takes place through a special organ called the placenta.
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
2.6K


