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Updated: Jan 17, 2026

Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids
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Published on: September 21, 2017

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通过多种反意义机制,桥梁核酸/DNA间隙作为基因表达的抑制剂

Angel J Magaña1, Kimberly Phan1, Jesse Lopez1

  • 1California State University Fullerton.

Research square
|September 15, 2025
PubMed
概括

锁定核酸 (LNA) 间隙显示了对基因沉默的双重作用潜力. 这些新型的反感性寡核酸可以通过RNase H或RNase P降解mRNA,提供增强的治疗策略.

关键词:
这就是RNase H.在RNase P中使用RNase P氨基甘油化是一种氨基甘油化.抗生素耐药性 抗生素耐药性这是一种反意义的反意义.桥梁核酸是一个桥梁.

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