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Updated: Jul 26, 2026

Incorporation of a Survivable Liver Biopsy Procedure in Mice to Assess Non-alcoholic Steatohepatitis NASH Resolution
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用孟德尔随机化,机器学习和外部验证来发现与代谢功能障碍相关的稳态性肝病的生物标志物

Gong Feng1, Giovanni Targher2,3, Christopher D Byrne4

  • 1Department of Infectious Diseases, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.

Journal of clinical and translational hepatology
|September 15, 2025
PubMed
概括

这项研究确定了代谢功能障碍相关的脂肪性肝病 (MASLD) 的因果分子和临床生物标志物. 血清总蛋白 (STP) 调解HLA-A效应并预测死亡率,而CNPY4和ENTPD6与肝癌存活率有关.

关键词:
有因果关系的生物标志物.机器学习 机器学习调解分析 调解分析门德尔的随机化与代谢功能障碍相关的脂肪肝疾病.非侵入性诊断是一种非侵入性诊断.预测 预后 预测 预测蛋白质组学是指蛋白质组学.

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