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相关概念视频

Brain Imaging01:14

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).

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相关实验视频

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A Method for Investigating Age-related Differences in the Functional Connectivity of Cognitive Control Networks Associated with Dimensional Change Card Sort Performance
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轮班工作和大脑年龄差距之间的关联:使用基于MRI的大脑年龄预测算法进行的神经成像研究.

Youjin Kim1, Joon Yul Choi2, Evgeny Petrovskiy3

  • 1Department of Preventive Medicine, College of Medicine, Chung-Ang University, Seoul, Republic of Korea.

Frontiers in aging neuroscience
|September 15, 2025
PubMed
概括

轮班工作似乎加快了大脑的衰老,轮班工作者的大脑年龄差距 (BAG) 更高表明了这一点. 更长的轮班工作时间可能表明神经适应性变化,需要进一步纵向调查.

关键词:
这就是为什么MRI是MRI.大脑大脑大脑的大脑大脑大脑年龄差距的大脑年龄差距大脑衰老 老龄化神经成像是一种神经成像.轮班工作是轮班工作.

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Whole-brain Segmentation and Change-point Analysis of Anatomical Brain MRI—Application in Premanifest Huntington's Disease
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相关实验视频

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科学领域:

  • 神经成像是一种神经成像.
  • 职业健康 职业健康 职业健康
  • 老年学是一门学科.

背景情况:

  • 轮班工作很普遍,并与不利的健康结果有关.
  • 现有研究表明,它对大脑结构和神经应激的影响.
  • 轮班工作对大脑衰老的直接影响尚不清楚.

研究的目的:

  • 研究轮班工作与大脑衰老之间的关联.
  • 使用大脑年龄差距 (BAG) 作为神经成像生物标志物.
  • 从MRI扫描中预测的大脑年龄与时间年龄进行比较.

主要方法:

  • 收集了来自113名医疗保健工作者的结构性MRI数据 (33个班次,80个白天).
  • 使用七种机器学习模型估计的大脑年龄.
  • 计算了BAG并进行了统计分析,调整了共变量.

主要成果:

  • 轮班工作者在同变量调整后显示出明显更高的BAG值,这表明大脑衰老加速.
  • 在对混因素进行控制后,有两种模型仍然具有重要意义.
  • 较长的轮班工作时间与BAG趋势的下降相关.

结论:

  • 轮班工作与加速的明显大脑衰老有关.
  • 随着长时间的暴露,BAG的减少可能表明适应性或选择性效应.
  • 强调需要在大脑健康研究中考虑职业暴露.