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恩科雷兰在增强屏障功能和减少敏感皮肤衰老迹象方面的有效性

Lina Wang¹, Caixia Wang¹, Liyuan Jiang¹

¹Research & Innovation Center, Proya Cosmetics Co. Ltd, Hangzhou, China.

Journal of cosmetic dermatology

|September 15, 2025

概括

新型成分混合物Encorelane有效降低炎症,并改善敏感皮肤的皮肤屏障功能. 它还可以对抗诸如纹之类的明显的衰老迹象,并增强皮肤坚硬度.

科学领域:

皮肤病学和化品科学
在体外和体外疗效研究.
皮肤屏障和衰老研究研究

背景情况:

敏感的皮肤需要专门的护理来增强屏障功能和减少炎症.
可见的衰老迹象需要对原蛋白合成和皮肤基质支持进行干预.

研究的目的:

为了评估Encorelane的疗效,Encorelane是一种新的糖类同位素,糖核糖和果糖酸糖的混合物.
评估Encorelane对敏感皮肤标志物和可见衰老迹象的影响.

主要方法:

在体外评估使用3D表皮模型 (EpiKutis) 与酸 (SLS) 诱导来测量细胞因子和屏障标记物.
通过水素3 (AQP3) 表达和抗纹功效对UVA/UVB暴露的液化在体外评价.
在体内进行了为期6周的双盲半面研究,对23名敏感皮肤受试者进行了评估,评估了临床效果与安慰剂的对比.

主要成果:

在体外:恩科雷兰显著降低了促炎性细胞因子 (IL-1α,TNF-α,IL-6,IL-8,PGE2) 和增加了障碍标记物 (FLG,LOR,TGM1) 和水合 (AQP3).
在体外:观察到 I,III,IV,VII,XVII类型的原和拉米宁5的显著增加,表明抗衰老潜力.
在体内:与安慰剂相比,Encorelane显著改善了皮肤间流失的水分 (TEWL),红色 (R2),坚硬 (F4) 和乌脚纹.

结论:

恩科雷兰在针对敏感皮肤的炎症和衰老迹象方面表现出显著的有效性.
配料混合物支持增强皮肤屏障功能和水合.
恩科雷兰为容易衰老的敏感皮肤提供了一种可行的皮肤化品解决方案.

关键词:

抗衰老的抗衰老的抗衰老的德莫化品公司这是一种炎症炎症炎症炎症.敏感的皮肤敏感的皮肤皮肤屏障的功能是皮肤的屏障.

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