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同行提供的推广与快速治疗途径的C型肝炎测试和治疗在无家可归的人群中
Gabriele Vojt1,2, Philippe Bonnet3, Jennifer Scott2
1National Institute for Health and Care Research (NIHR) Health Protection Research Unit in Evaluation and Behavioural Science, University of Bristol, Bristol, UK.
Journal of viral hepatitis
|September 15, 2025
概括
一个由同行领导的型肝炎病毒 (HCV) 测试和治疗计划成功地到达了英格兰的无家可归者. 这种创新途径在弱势群体中实现了较高的治疗吸收率和治疗完成率.
科学领域:
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
- 社会医学 社会医学
背景情况:
- 型肝炎病毒 (HCV) 不成比例地影响边缘化人口,包括无家可归的人.
- 向无家可归的人提供基本的医疗保健服务,如HCV检测和治疗,面临重大挑战.
- 需要创新的,以社区为基础的方法来改善这一人口中的HCV结果.
研究的目的:
- 描述为无家可归的个人共同开发和实施以同行为主导的,快速的HCV检测和治疗途径.
- 评估这种途径在边缘化人口中发现,测试和治疗HCV病例的有效性.
- 评估这个特定群体内的治疗开始和完成率.
主要方法:
- 一名经过培训的同行工作者与当地服务和医疗保健工作人员合作,在无家可归者收容所进行HCV检测和治疗活动.
- 提供了点照顾的HCV抗体和RNA测试,以及同行教育和支持.
- 感染病毒的个体接受了由临床HCV专家护士处方的即时治疗.
主要成果:
- 检测了140名无家可归的人,其中51.4%的检测结果为HCV抗体阳性,30.0%的HCVRNA阳性.
- 所有参与者都报告了注射药物使用史;大多数是男性 (75.0%),平均年龄为39岁,白人 (89.4%).
- 治疗开始率为100%,已知治疗完成率为92.3%,在2周内治疗开始率为57.1%.
结论:
- 共同开发的,同行领导的HCV测试和治疗途径在识别,测试和治疗无家可归人群中的HCV方面表现出显著的希望.
- 这种模式有效地吸引了难以接触的人群,促进了高率的治疗开始和完成.
- 以同行为主导的干预是改善边缘化社区HCV护理的可行和有效策略.
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